- translational research in sarcoma
- clinical trials including novel diagnostic approaches and agents
Professor van der Graaf was trained and worked as a medical oncologist in university medical centres in Groningen and Nijmegen in the Netherlands.
In 2007 she was appointed as Professor of Medical Oncology at Radboudumc in Nijmegen. Before she joined the Sarcoma team at The Royal Marsden and was appointed as Professor of Personalised Oncology at the Institute of Cancer Research (ICR) in 2015 she headed the Department of Medical Oncology at the Radboud University Medical Centre, supervised many PhD students and was chair of a national program for Young Cancer patients (AYA4 net) in the Netherlands.
She was chair of the EORTC Soft Tissue and Bone Sarcoma Groups from 2011-2014, and remains a board member. She led a pivotal phase 3 study (PALETTE) in pazopanib which led to the drug's FDA and EMA registration for soft tissue sarcomas.
Her main interests are in translational research in sarcoma, where observations in clinical practice can be brought back to the lab and vice versa, and on clinical trials including novel diagnostic approaches and agents.
She is passionate about finding better treatments for patients with bone and soft tissue sarcomas and about research focused on improvement of sarcoma patients’ quality of life.