- Cancer predisposition gene and testing, including BRCA1 and BRCA2
Professor Nazneen Rahman qualified in medicine from Oxford University in 1991, and undertook her general medical training in Oxford and London, and her specialist training in Cardiff. She completed a PhD in Molecular Genetics at The Institute of Cancer Research in 1999 under the supervision of Professor Michael Stratton. She completed her Certificate of Completion of Specialist Training in Clinical Genetics in 2001.
In her clinical role, she is responsible for the cancer genetics service at The Royal Marsden, and she practises as a Consultant Clinical Geneticist at The Royal Marsden.
In her research role, she is one of the UK’s leading researchers in cancer predisposition genes with particular interests in breast, ovarian, testicular and childhood cancers. In addition to identifying numerous genes and genetic factors that increase the risk of cancers developing, she has used this research to develop clinical improvements in patient care.
She has continually striven to make the most effective use of the rapid development of sequencing technology in recent years to reveal further aspects of the genetic architecture of cancer and to develop new testing methods. Professor Rahman is currently leading the Mainstreaming Cancer Genetics Programme, the aim of which is to make genetic testing available to more patients as part of their routine cancer care.
Professor Rahman provides advice to clinicians from across the world about rare cancer genetic syndromes, and integrates the molecular and clinical data from her research to produce diagnostic and management guidance for rare cancer-associated conditions.