Haematology diagnostics (SIHMDS)

State-of-the-art technology and world-class expertise combine to provide The Royal Marsden’s Specialist Integrated Haematology Malignancies Diagnostic Service (SIHMDS).

Our histopathology, molecular diagnostics, immunophenotyping and cytogenetics laboratories share specialised knowledge to produce integrated assessments for all types of leukaemia, lymphoma, myeloma and related disorders.

A team of six haematologists, three haemato-pathologists and more than 30 scientists work together to provide an integrated approach for the diagnosis, prognosis and monitoring of haematological malignancies.

Algorithms are used to best provide an accurate diagnosis and the necessary prognostic information to enable personalised treatment plans for patients. A diagnostic report provides expert scientific interpretation of the results with a consultant's final diagnosis, in accordance with WHO classification.

The service is compliant with the National Institute for Health and Care Excellence (NICE) improving outcomes guidance. It aims to provide targeted, cost-effective and timely diagnostic results to improve patient outcomes. It is available to NHS, private and research clients in the UK and overseas.

The laboratories also offer individual, stand-alone testing. We offer free IDH1 and IDH2 testing for adult patients with AML either at presentation or at relapse. You can either use our standard request form for these or the specific IDH1 and IDH2 request form from the downloads section below.

We also offer free TP53 mutation testing supported by Janssen-Cilag Ltd. (Please note there must be a contract in place with Janssen in order to access free TP53 mutation testing. Please contact Peter Hillan, Health Economy Liaison Manager for further information) Further information is available in the document in the downloads section below.

Read our full test repertoire (PDF) here. To request a Haematological Malignancies Diagnostic Service test, please contact the haematology diagnostics Business Manager for a request form.

Order and View web portal

This secure online system allows users to order tests, track their samples and view all test results directly.

Contact the haematology diagnostics service

Healthcare providers: for enquiries, please contact our haematology diagnostics Business Manager.

Patients: for private second opinions on diagnostic biopsy material or any general enquiries concerning the tests we offer, please email us at sihmds@rmh.nhs.uk.