What is a clinical trial?

A clinical trial is a carefully designed investigation into the effects of a diagnostic test, treatment or style of care, for example:

Tests

  • Screening: to find ways of detecting cancer at an earlier stage.
  • Diagnosing cancer: looking at new tests or scans that can help detect cancer in a better way.

Treatments

  • Treatment with new drugs or combinations of drugs, or new ways of giving drug treatments, surgery or radiotherapy.
  • A new treatment may be compared with an older and more accepted treatment to find out which works better.
  • The question may be “Is the treatment being given in the best way?” For example, comparing how frequently drugs are given – once a week or once a month.
  • Monitoring the progress of treatment.

Supportive care

  • Controlling symptoms, such as pain, nausea or shortness of breath. For example, a trial may look at new drugs or complementary therapies.
  • The researcher may want to discover how best to provide support by finding out how treatment affects your everyday life and activities.

Genetics

  • To help learn more about the role genes play in cancer.

Preventing cancer

  • These trials are conducted with healthy people who have not had cancer. For example, they may look at drugs, vitamins, foods to reduce risk, etc.

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www.royalmarsden.nhs.uk/cancer-information/clinical-trials/what

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